Serum of myeloproliferative neoplasms stimulates hematopoietic stem and progenitor cells

BACKGROUND: Myeloproliferative neoplasms (MPN)—such as polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis (MF)—are typically diseases of the elderly caused by acquired somatic mutations. However, it is largely unknown how the malignant clone interferes with normal hematopoiesi...

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Publicat a:PLoS One
Autors principals: Lubberich, Richard K., Walenda, Thomas, Goecke, Tamme W., Strathmann, Klaus, Isfort, Susanne, Brümmendorf, Tim H., Koschmieder, Steffen, Wagner, Wolfgang
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979002/
https://ncbi.nlm.nih.gov/pubmed/29851963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197233
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