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Targeting tissue factor on tumor vascular endothelial cells and tumor cells for immunotherapy in mouse models of prostatic cancer
The efficacy and safety of an immunoconjugate (icon) molecule, composed of a mutated mouse factor VII (mfVII) targeting domain and the Fc effector domain of an IgG1 Ig (mfVII/Fc icon), was tested with a severe combined immunodeficient (SCID) mouse model of human prostatic cancer and an immunocompete...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC59788/ https://ncbi.nlm.nih.gov/pubmed/11593034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.201420298 |
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