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Retroviral-mediated transmission of a mouse VL30 RNA to human melanoma cells promotes metastasis in an immunodeficient mouse model

Infection of a human melanoma cell line by a retroviral vector resulted in transmission of a mouse VL30 (mVL30-1) retroelement RNA to some of the cells infected by the retrovirus, followed by synthesis, integration, and expression of the mVL30-1 cDNA. One vector carried a tissue factor (TF) transgen...

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Detalhes bibliográficos
Main Authors: Song, Xu, Wang, Baiyang, Bromberg, Michael, Hu, Zhiwei, Konigsberg, William, Garen, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122938/
https://ncbi.nlm.nih.gov/pubmed/11959915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092112199
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