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Roles of PSF protein and VL30 RNA in reversible gene regulation
The mammalian protein PSF contains a DNA-binding domain (DBD) that coordinately represses multiple oncogenic genes in human cell lines, indicating a role for PSF as a human tumor-suppressor protein. PSF also contains two RNA-binding domains (RBD) that form a complex with a noncoding VL30 retroelemen...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1189330/ https://ncbi.nlm.nih.gov/pubmed/16079199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505179102 |
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