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Roles of PSF protein and VL30 RNA in reversible gene regulation

The mammalian protein PSF contains a DNA-binding domain (DBD) that coordinately represses multiple oncogenic genes in human cell lines, indicating a role for PSF as a human tumor-suppressor protein. PSF also contains two RNA-binding domains (RBD) that form a complex with a noncoding VL30 retroelemen...

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Detalhes bibliográficos
Main Authors: Song, Xu, Sun, Ying, Garen, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1189330/
https://ncbi.nlm.nih.gov/pubmed/16079199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505179102
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