Cardiovascular, skeletal, and renal defects in mice with a targeted disruption of the Pkd1 gene

Autosomal dominant polycystic kidney disease (ADPKD) is characterized by cyst formation in the kidney, liver, and pancreas and is associated often with cardiovascular abnormalities such as hypertension, mitral valve prolapse, and intracranial aneurysms. It is caused by mutations in PKD1 or PKD2, enc...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Boulter, Catherine, Mulroy, Sharon, Webb, Sandra, Fleming, Stewart, Brindle, Kevin, Sandford, Richard
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC59787/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11593033/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.211191098
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