Cardiovascular, skeletal, and renal defects in mice with a targeted disruption of the Pkd1 gene

Autosomal dominant polycystic kidney disease (ADPKD) is characterized by cyst formation in the kidney, liver, and pancreas and is associated often with cardiovascular abnormalities such as hypertension, mitral valve prolapse, and intracranial aneurysms. It is caused by mutations in PKD1 or PKD2, enc...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Boulter, Catherine, Mulroy, Sharon, Webb, Sandra, Fleming, Stewart, Brindle, Kevin, Sandford, Richard
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2001
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC59787/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11593033/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.211191098
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