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The discovery of novel HDAC3 inhibitors via virtual screening and in vitro bioassay
Histone deacetylase 3 (HDAC3) is a potential target for the treatment of human diseases such as cancers, diabetes, chronic inflammation and neurodegenerative diseases. Previously, we proposed a virtual screening (VS) pipeline named “Hypo1_FRED_SAHA-3” for the discovery of HDAC3 inhibitors (HDAC3Is)...
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| Publicado no: | J Enzyme Inhib Med Chem |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5978667/ https://ncbi.nlm.nih.gov/pubmed/29464997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1437156 |
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