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Using voltage‐sensor toxins and their molecular targets to investigate Na(V)1.8 gating
Voltage‐gated sodium (Na(V)) channel gating is a complex phenomenon which involves a distinct contribution of four integral voltage‐sensing domains (VSDI, VSDII, VSDIII and VSDIV). Utilizing accrued pharmacological and structural insights, we build on an established chimera approach to introduce ani...
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| Udgivet i: | J Physiol |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5978285/ https://ncbi.nlm.nih.gov/pubmed/29193176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP275102 |
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