Cargando...

A novel gene expression analytics-based approach to structure aided design of rexinoids for development as next-generation cancer therapeutics

Rexinoids are powerful ligands that bind to retinoid-X-receptors (RXRs) and show great promise as therapeutics for a wide range of diseases, including cancer. However, only one rexinoid, bexarotene (Targretin TM) has been successfully transitioned from the bench to the clinic and used to treat cutan...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Steroids
Autores principales: Hanish, Bentley J., Hackney Price, Jennifer F., Kaneko, Ichiro, Ma, Ning, van der Vaart, Arjan, Wagner, Carl E., Jurutka, Peter W., Marshall, Pamela A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5977990/
https://ncbi.nlm.nih.gov/pubmed/29704526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2018.04.009
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!