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A novel gene expression analytics-based approach to structure aided design of rexinoids for development as next-generation cancer therapeutics
Rexinoids are powerful ligands that bind to retinoid-X-receptors (RXRs) and show great promise as therapeutics for a wide range of diseases, including cancer. However, only one rexinoid, bexarotene (Targretin TM) has been successfully transitioned from the bench to the clinic and used to treat cutan...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Steroids |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5977990/ https://ncbi.nlm.nih.gov/pubmed/29704526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2018.04.009 |
| Ετικέτες: |
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