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Nuclear relocation of a transactivator subunit precedes target gene activation

Murine erythroleukemia (MEL) cells are a model system to study reorganization of the eukaryotic nucleus during terminal differentiation. Upon chemical induction, MEL cells undergo erythroid differentiation, leading to activation of globin gene expression. Both processes strongly depend on the transc...

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Bibliographic Details
Main Authors: Francastel, Claire, Magis, Wendy, Groudine, Mark
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2001
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC59778/
https://ncbi.nlm.nih.gov/pubmed/11593025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.211444898
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