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Cell cycle accumulation of the proliferating cell nuclear antigen PCN-1 transitions from continuous in the adult germline to intermittent in the early embryo of C. elegans

BACKGROUND: The proliferating cell nuclear antigen (PCNA or PCN-1 in C. elegans), an essential processivity factor for DNA polymerase δ, has been widely used as a marker of S-phase. In C. elegans early embryos, PCN-1 accumulation is cyclic, localizing to the nucleus during S-phase and the cytoplasm...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Dev Biol
Hauptverfasser: Kocsisova, Zuzana, Kornfeld, Kerry, Schedl, Tim
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5977546/
https://ncbi.nlm.nih.gov/pubmed/29848313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12861-018-0171-7
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