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ROLE OF THE C-TERMINUS MOBILE DOMAIN OF CARDIAC TROPONIN I IN THE REGULATION OF THIN FILAMENT ACTIVATION IN SKINNED PAPILLARY MUSCLE STRIPS
The C-terminus mobile domain of cTnI (cTnI-MD) is a highly conserved region which stabilizes the actin-cTnI interaction during the diastole. Upon Ca(2+)-binding to cTnC, cTnI-MD participates in a regulatory switching that involves cTnI to switch from interacting with actin toward interacting with th...
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| Publicado no: | Arch Biochem Biophys |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5977403/ https://ncbi.nlm.nih.gov/pubmed/29704484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2018.04.014 |
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