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Quantitative mutant analysis of viral quasispecies by chip-based matrix-assisted laser desorption/ ionization time-of-flight mass spectrometry

RNA viruses exist as quasispecies, heterogeneous and dynamic mixtures of mutants having one or more consensus sequences. An adequate description of the genomic structure of such viral populations must include the consensus sequence(s) plus a quantitative assessment of sequence heterogeneities. For e...

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Detalhes bibliográficos
Main Authors: Amexis, Georgios, Oeth, Paul, Abel, Kenneth, Ivshina, Anna, Pelloquin, Francois, Cantor, Charles R., Braun, Andreas, Chumakov, Konstantin
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC59774/
https://ncbi.nlm.nih.gov/pubmed/11593021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.211423298
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