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Influence of Maternal Aging on Mitochondrial Heterogeneity, Inheritance, and Function in Oocytes and Preimplantation Embryos

Contrasting the equal contribution of nuclear genetic material from maternal and paternal sources to offspring, passage of mitochondria, and thus mitochondrial DNA (mtDNA), is uniparental through the egg. Since mitochondria in eggs are ancestral to all somatic mitochondria of the next generation and...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Woods, Dori C., Khrapko, Konstantin, Tilly, Jonathan L.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5977205/
https://ncbi.nlm.nih.gov/pubmed/29883421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9050265
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