Maternal depletion of CTCF reveals multiple functions during oocyte and preimplantation embryo development

CTCF is a multifunctional nuclear factor involved in epigenetic regulation. Despite recent advances that include the systematic discovery of CTCF-binding sites throughout the mammalian genome, the in vivo roles of CTCF in adult tissues and during embryonic development are largely unknown. Using tran...

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Autores principales: Wan, Le-Ben, Pan, Hua, Hannenhalli, Sridhar, Cheng, Yong, Ma, Jun, Fedoriw, Andrew, Lobanenkov, Victor, Latham, Keith E., Schultz, Richard M., Bartolomei, Marisa S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596970/
https://ncbi.nlm.nih.gov/pubmed/18614575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.024539
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