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Inhibition of Akt/mTOR/p70S6K Signaling Activity With Huangkui Capsule Alleviates the Early Glomerular Pathological Changes in Diabetic Nephropathy

Huangkui capsule (HKC), a Chinese modern patent medicine extracted from Abelmoschus manihot (L.) medic, has been widely applied to clinical therapy in the early diabetic nephropathy (DN) patients. However, it remains elusive whether HKC can ameliorate the inchoate glomerular injuries in hyperglycemi...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Wu, Wei, Hu, Wei, Han, Wen-Bei, Liu, Ying-Lu, Tu, Yue, Yang, Hai-Ming, Fang, Qi-Jun, Zhou, Mo-Yi, Wan, Zi-Yue, Tang, Ren-Mao, Tang, Hai-Tao, Wan, Yi-Gang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976825/
https://ncbi.nlm.nih.gov/pubmed/29881349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00443
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