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Losartan Affects Glomerular AKT and mTOR Phosphorylation in an Experimental Model of Type 1 Diabetic Nephropathy

The AKT-mTOR pathway is activated in diabetic nephropathy. Renin-angiotensin system modulators exert beneficial effects on the diabetic kidney. We explored the action of losartan on AKT-mTOR phosphorylation in glomeruli and podocytes. Diabetes mellitus was induced to Sprague-Dawley rats by streptozo...

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Detalhes bibliográficos
Main Authors: Mavroeidi, Vasiliki, Petrakis, Ioannis, Stylianou, Kostas, Katsarou, Theodora, Giannakakis, Konstantinos, Perakis, Kostas, Vardaki, Eleftheria, Stratigis, Spyridon, Ganotakis, Emmanuel, Papavasiliou, Stathis, Daphnis, Eugenios
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715326/
https://ncbi.nlm.nih.gov/pubmed/23456824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155413482925
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