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Promoter free allylation of trichloroacetimidates with allyltributylstannanes under thermal conditions to access the common 1,1’-diarylbutyl pharmacophore()
1,1’-Diarylbutyl groups are a common pharmacophore found in many biologically active small molecules. To access these systems under mild conditions, the reaction of diarylmethyl trichloroacetimidates with allyltributylstannanes was explored. Simply heating allyltributylstannane with the trichloroace...
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| Gepubliceerd in: | Org Biomol Chem |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5976556/ https://ncbi.nlm.nih.gov/pubmed/29766199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ob00687c |
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