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Multiplex tandem mass spectrometry assay for newborn screening of X-linked adrenoleukodystrophy, biotinidase deficiency, and galactosemia with flexibility to assay other enzyme assays and biomarkers

All States screen for biotinidase deficiency and galactosemia, and X-linked adrenoleukodystrophy (X-ALD) has recently been added to the Recommended Uniform Screening Panel (RUSP). We sought to consolidate these tests by combining them into a single multiplex tandem mass spectrometry assay as well as...

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Detalhes bibliográficos
Publicado no:Mol Genet Metab
Main Authors: Hong, Xinying, Kumar, Arun Babu, Scott, C. Ronald, Gelb, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976550/
https://ncbi.nlm.nih.gov/pubmed/29680633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2018.03.012
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