Human Hepatocyte Transplantation Corrects the Inherited Metabolic Liver Disorder Arginase Deficiency in Mice

The transplantation, engraftment, and expansion of primary hepatocytes have the potential to be an effective therapy for metabolic disorders of the liver including those of nitrogen metabolism. To date, such methods for the treatment of urea cycle disorders in murine models has only been minimally e...

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Veröffentlicht in:Mol Genet Metab
Hauptverfasser: Angarita, Stephanie A. K., Truong, Brian, Khoja, Suhail, Nitzahn, Matthew, Rajbhandari, Abha K., Zhuravka, Irina, Duarte, Sergio, Lin, Michael G., Lam, Alex K., Cederbaum, Stephen D., Lipshutz, Gerald S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976549/
https://ncbi.nlm.nih.gov/pubmed/29724658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2018.04.005
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