Right Ventricular Myofilament Functional Differences in Humans with Systemic Sclerosis-associated versus Idiopathic Pulmonary Arterial Hypertension

BACKGROUND: Patients with systemic sclerosis-associated pulmonary arterial hypertension (SSc-PAH) have a far worse prognosis than those with idiopathic PAH (IPAH). In the intact heart, SSc-PAH exhibits depressed rest and reserve right ventricular (RV) contractility as compared to IPAH. We tested whe...

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Vydáno v:Circulation
Hlavní autoři: Hsu, Steven, Kokkonen-Simon, Kristen M., Kirk, Jonathan A., Kolb, Todd M., Damico, Rachel L., Mathai, Stephen C., Mukherjee, Monica, Shah, Ami A., Wigley, Fredrick M., Margulies, Kenneth B., Hassoun, Paul M., Halushka, Marc K., Tedford, Ryan J., Kass, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976528/
https://ncbi.nlm.nih.gov/pubmed/29352073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.117.033147
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