Right Ventricular Myofilament Functional Differences in Humans with Systemic Sclerosis-associated versus Idiopathic Pulmonary Arterial Hypertension

BACKGROUND: Patients with systemic sclerosis-associated pulmonary arterial hypertension (SSc-PAH) have a far worse prognosis than those with idiopathic PAH (IPAH). In the intact heart, SSc-PAH exhibits depressed rest and reserve right ventricular (RV) contractility as compared to IPAH. We tested whe...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Hsu, Steven, Kokkonen-Simon, Kristen M., Kirk, Jonathan A., Kolb, Todd M., Damico, Rachel L., Mathai, Stephen C., Mukherjee, Monica, Shah, Ami A., Wigley, Fredrick M., Margulies, Kenneth B., Hassoun, Paul M., Halushka, Marc K., Tedford, Ryan J., Kass, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976528/
https://ncbi.nlm.nih.gov/pubmed/29352073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.117.033147
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