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Identification of a critical sulfation in chondroitin that inhibits axonal regeneration
The failure of mammalian CNS neurons to regenerate their axons derives from a combination of intrinsic deficits and extrinsic factors. Following injury, chondroitin sulfate proteoglycans (CSPGs) within the glial scar inhibit axonal regeneration, an action mediated by the sulfated glycosaminoglycan (...
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| 出版年: | eLife |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5976435/ https://ncbi.nlm.nih.gov/pubmed/29762123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37139 |
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