Lysines in RNA polymerase II C-terminal domain contribute to TAF15 fibril recruitment

Many cancer-causing chromosomal translocations result in transactivating protein products encoding FET family (FUS, EWSR1, TAF15) low complexity (LC) domains fused to a DNA-binding domain from one of several transcription factors. Recent work demonstrates that higher order assemblies of FET LC domai...

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Publicado en:Biochemistry
Autores principales: Janke, Abigail M., Seo, Da Hee, Rahmanian, Vahid, Conicella, Alexander E., Mathews, Kaylee L., Burke, Kathleen A., Mittal, Jeetain, Fawzi, Nicolas L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5975632/
https://ncbi.nlm.nih.gov/pubmed/28945358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00310
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