Functional analysis of mutant and wild-type Drosophila origin recognition complex
The origin recognition complex (ORC) is the DNA replication initiator protein in eukaryotes. We have reconstituted a functional recombinant Drosophila ORC and compared activities of the wild-type and several mutant ORC variants. Drosophila ORC is an ATPase, and our studies show that the ORC1 subunit...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC59756/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11593009/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.211342798 |
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