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Functional analysis of mutant and wild-type Drosophila origin recognition complex

The origin recognition complex (ORC) is the DNA replication initiator protein in eukaryotes. We have reconstituted a functional recombinant Drosophila ORC and compared activities of the wild-type and several mutant ORC variants. Drosophila ORC is an ATPase, and our studies show that the ORC1 subunit...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Chesnokov, Igor, Remus, Dirk, Botchan, Michael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2001
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Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC59756/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11593009/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.211342798
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