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Knock-down of LRP/LR promotes apoptosis in early and late stage colorectal carcinoma cells via caspase activation

BACKGROUND: Cancer remains one of the leading causes of death around the world, where incidence and mortality rates are at a constant increase. Tumourigenic cells are characteristically seen to over-express the 37 kDa/67 kDa laminin receptor (LRP/LR) compared to their normal cell counterparts. This...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Vania, Leila, Rebelo, Thalia M., Ferreira, Eloise, Weiss, Stefan F. T.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5975593/
https://ncbi.nlm.nih.gov/pubmed/29843646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4531-2
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