Association Between ABCB1 Polymorphism and Stable Warfarin Dose Requirements in Brazilian Patients

The ideal dose of the oral anticoagulant warfarin varies widely among patients, mainly due to genetic factors. Genetic variations that impact warfarin pharmacokinetics and the vitamin K cycle are plausible candidates for being associated with warfarin dose requirements. Therefore, the aim of this st...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Tavares, Letícia C., Marcatto, Leiliane R., Soares, Renata A. G., Krieger, Jose E., Pereira, Alexandre C., Santos, Paulo C. J. L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5975540/
https://ncbi.nlm.nih.gov/pubmed/29875668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00542
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