Nuclear receptor gene polymorphisms and warfarin dose requirements in the Quebec Warfarin Cohort

Warfarin is primarily metabolized by cytochrome 2C9, encoded by gene CYP2C9. Here, we investigated whether variants in nuclear receptor genes which regulate the expression of CYP2C9 are associated with warfarin response. We used data from 906 warfarin users from the Quebec Warfarin Cohort (QWC) and...

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書誌詳細
出版年:Pharmacogenomics J
主要な著者: Shahabi, Payman, Lamothe, Félix, Dumas, Stéphanie, Rouleau-Mailloux, Étienne, Feroz Zada, Yassamin, Provost, Sylvie, Asselin, Geraldine, Mongrain, Ian, Valois, Diane, Gaulin Marion, Marie-Josée, Lemieux Perreault, Louis-Philippe, Perreault, Sylvie, Dubé, Marie-Pierre
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462825/
https://ncbi.nlm.nih.gov/pubmed/29298995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41397-017-0005-1
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