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Co-transfer of tumor-specific effector and memory CD8+ T cells enhances the efficacy of adoptive melanoma immunotherapy in a mouse model
BACKGROUND: Adoptive cell transfer (ACT) is a promising cancer immunotherapeutic strategy that remains ineffective for a large subset of patients. ACT with memory CD8+ T cells (T(mem)) has been shown to have superior efficacy compared to traditional ACT with effector CD8+ T cells (T(eff)). T(eff) an...
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| Опубликовано в: : | J Immunother Cancer |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5975512/ https://ncbi.nlm.nih.gov/pubmed/29843822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-018-0358-2 |
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