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Sources of spontaneous mutagenesis in bacteria

Mutations in an organism’s genome can arise spontaneously, i.e., in the absence of exogenous stress and prior to selection. Mutations are often neutral or deleterious to individual fitness, but can also provide genetic diversity driving evolution. Mutagenesis in bacteria contributes to the already s...

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Bibliographic Details
Published in:Crit Rev Biochem Mol Biol
Main Authors: Schroeder, Jeremy W., Yeesin, Ponlkrit, Simmons, Lyle A., Wang, Jue D.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5975382/
https://ncbi.nlm.nih.gov/pubmed/29108429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2017.1394262
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