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Redox imbalance stress in diabetes mellitus: Role of the polyol pathway
In diabetes mellitus, the polyol pathway is highly active and consumes approximately 30% glucose in the body. This pathway contains 2 reactions catalyzed by aldose reductase (AR) and sorbitol dehydrogenase, respectively. AR reduces glucose to sorbitol at the expense of NADPH, while sorbitol dehydrog...
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| Pubblicato in: | Animal Model Exp Med |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5975374/ https://ncbi.nlm.nih.gov/pubmed/29863179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ame2.12001 |
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