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Redox imbalance stress in diabetes mellitus: Role of the polyol pathway

In diabetes mellitus, the polyol pathway is highly active and consumes approximately 30% glucose in the body. This pathway contains 2 reactions catalyzed by aldose reductase (AR) and sorbitol dehydrogenase, respectively. AR reduces glucose to sorbitol at the expense of NADPH, while sorbitol dehydrog...

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Detalles Bibliográficos
Publicado en:Animal Model Exp Med
Autor Principal: Yan, Liang‐jun
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5975374/
https://ncbi.nlm.nih.gov/pubmed/29863179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ame2.12001
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