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Roles of Pyruvate, NADH, and Mitochondrial Complex I in Redox Balance and Imbalance in β Cell Function and Dysfunction

Pancreatic β cells not only use glucose as an energy source, but also sense blood glucose levels for insulin secretion. While pyruvate and NADH metabolic pathways are known to be involved in regulating insulin secretion in response to glucose stimulation, the roles of many other components along the...

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Bibliographic Details
Published in:J Diabetes Res
Main Authors: Luo, Xiaoting, Li, Rongrong, Yan, Liang-Jun
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629043/
https://ncbi.nlm.nih.gov/pubmed/26568959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/512618
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