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Functional Relevance of the Transmembrane Domain and Cytoplasmic Tail of the Pseudorabies Virus Glycoprotein H for Membrane Fusion

Herpesvirus membrane fusion depends on the core fusion machinery, comprised of glycoproteins B (gB) and gH/gL. Although gB structurally resembles autonomous class III fusion proteins, it strictly depends on gH/gL to drive membrane fusion. Whether the gH/gL complex needs to be membrane anchored to fu...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Vallbracht, Melina, Fuchs, Walter, Klupp, Barbara G., Mettenleiter, Thomas C.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974499/
https://ncbi.nlm.nih.gov/pubmed/29618646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00376-18
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