Mutations in Pseudorabies Virus Glycoproteins gB, gD, and gH Functionally Compensate for the Absence of gL

Entry of herpesviruses depends on the combined action of viral glycoprotein B (gB) and the heterodimeric gH/gL complex, which are activated by binding of the virion to specific cellular receptors. While gB carries signatures of a bona fide fusion protein, efficient membrane fusion requires gH/gL. Ho...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Schröter, Christina, Vallbracht, Melina, Altenschmidt, Jan, Kargoll, Sabrina, Fuchs, Walter, Klupp, Barbara G., Mettenleiter, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810696/
https://ncbi.nlm.nih.gov/pubmed/26656712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02739-15
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