Improvement of the Dengue Virus (DENV) Nonhuman Primate Model via a Reverse Translational Approach Based on Dengue Vaccine Clinical Efficacy Data against DENV-2 and -4

Recent data obtained with the live-attenuated tetravalent dengue CYD-TDV vaccine showed higher protective efficacy against dengue virus type 4 (DENV-4) than against DENV-2. In contrast, results from previous studies in nonhuman primates predicted comparable high levels of protection against each ser...

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Publicado en:J Virol
Autores principales: Barban, Veronique, Mantel, Nathalie, De Montfort, Aymeric, Pagnon, Anke, Pradezynski, Fabrine, Lang, Jean, Boudet, Florence
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974474/
https://ncbi.nlm.nih.gov/pubmed/29593041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00440-18
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