Multilevel Differential Control of Hormone Gene Expression Programs by hnRNP L and LL in Pituitary Cells

The pituitary-derived somatolactotrophe GH(3) cells secrete both growth hormone (GH) and prolactin (PRL). We have found that the hnRNP L and L-like (LL) paralogs differentially regulate alternative splicing of genes in these cells. Here, we show that hnRNP L is essential for PRL only, but LL is esse...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Lei, Lei, Cao, Wenguang, Liu, Ling, Das, Urmi, Wu, Yujia, Liu, Guodong, Sohail, Muhammad, Chen, Yangjun, Xie, Jiuyong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974433/
https://ncbi.nlm.nih.gov/pubmed/29610151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00651-17
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