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Multilevel Differential Control of Hormone Gene Expression Programs by hnRNP L and LL in Pituitary Cells
The pituitary-derived somatolactotrophe GH(3) cells secrete both growth hormone (GH) and prolactin (PRL). We have found that the hnRNP L and L-like (LL) paralogs differentially regulate alternative splicing of genes in these cells. Here, we show that hnRNP L is essential for PRL only, but LL is esse...
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| Veröffentlicht in: | Mol Cell Biol |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5974433/ https://ncbi.nlm.nih.gov/pubmed/29610151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00651-17 |
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