The Phosphatase PTPL1 Is Required for PTEN-Mediated Regulation of Apical Membrane Size

PTEN is a tumor suppressor that is frequently lost in epithelial malignancies. A part of the tumor-suppressive properties of PTEN is attributed to its function in cell polarization and consequently its role in maintaining epithelial tissue integrity. However, surprisingly little is known about the f...

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Publicat a:Mol Cell Biol
Autors principals: Bruurs, Lucas J. M., van der Net, Mirjam C., Zwakenberg, Susan, Rosendahl Huber, Axel K. M., Post, Anneke, Zwartkruis, Fried J., Bos, Johannes L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974425/
https://ncbi.nlm.nih.gov/pubmed/29581186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00102-18
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