The association between cancer family history and ovarian cancer risk in BRCA1/2 mutation carriers: can it be explained by the mutation position?

This observational study aimed to investigate whether the reported association between family history (FH) of breast cancer (BC) or ovarian cancer (OC) and OC risks in BRCA1/2 mutation carriers can be explained by mutation position on the gene. In total, 3310 female BRCA1/2 mutation carriers partici...

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Detalhes bibliográficos
Publicado no:Eur J Hum Genet
Main Authors: Teixeira, Natalia, van der Hout, Annemieke, Oosterwijk, Jan C., Vos, Janet R., Devilee, Peter, van Engelen, Klaartje, Meijers-Heijboer, Hanne, van der Luijt, Rob B., Kriege, Mieke, Mensenkamp, Arjen R., Rookus, Matti A., van Roozendaal, Kees E., Mourits, Marian J. E., de Bock, Geertruida H.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974362/
https://ncbi.nlm.nih.gov/pubmed/29483665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-018-0111-9
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