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Expansion of human primary hepatocytes in vitro through their amplification as liver progenitors in a 3D organoid system

Despite decades of investigation on the proliferation of adult human primary hepatocytes, their expansion in vitro still remains challenging. To later be able to consider hepatocytes as a cell therapy alternative or bridge to liver transplantation, dramatically impeded by a shortage in liver donors,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Garnier, Delphine, Li, Ruoya, Delbos, Frédéric, Fourrier, Angélique, Collet, Camille, Guguen-Guillouzo, Christiane, Chesné, Christophe, Nguyen, Tuan Huy
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974235/
https://ncbi.nlm.nih.gov/pubmed/29844473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26584-1
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