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Animal Models for Coffin-Lowry Syndrome: RSK2 and Nervous System Dysfunction
Loss of function mutations in the rsk2 gene cause Coffin-Lowry syndrome (CLS), which is associated with multiple symptoms including severe mental disabilities. Despite the characterization of ribosomal S6 kinase 2 (RSK2) as a protein kinase acting as a downstream effector of the well characterized E...
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| Udgivet i: | Front Behav Neurosci |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5974046/ https://ncbi.nlm.nih.gov/pubmed/29875643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2018.00106 |
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