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Animal Models for Coffin-Lowry Syndrome: RSK2 and Nervous System Dysfunction

Loss of function mutations in the rsk2 gene cause Coffin-Lowry syndrome (CLS), which is associated with multiple symptoms including severe mental disabilities. Despite the characterization of ribosomal S6 kinase 2 (RSK2) as a protein kinase acting as a downstream effector of the well characterized E...

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Detalhes bibliográficos
Publicado no:Front Behav Neurosci
Main Authors: Fischer, Matthias, Raabe, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974046/
https://ncbi.nlm.nih.gov/pubmed/29875643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2018.00106
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