Glucagon-like peptide 1 receptor (GLP-1R) expression by nerve fibres in inflammatory bowel disease and functional effects in cultured neurons

INTRODUCTION: Glucagon like-peptide 1 receptor (GLP-1R) agonists diminish appetite and may contribute to the weight loss in inflammatory bowel disease (IBD). OBJECTIVES: The aim of this study was to determine, for the first time, the expression of GLP-1R by colon nerve fibres in patients with IBD, a...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Anand, Uma, Yiangou, Yiangos, Akbar, Ayesha, Quick, Tom, MacQuillan, Anthony, Fox, Mike, Sinisi, Marco, Korchev, Yuri E., Jones, Ben, Bloom, Steve R., Anand, Praveen
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5973579/
https://ncbi.nlm.nih.gov/pubmed/29813107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198024
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