Co-culture of Marine Invertebrate-Associated Bacteria and Interdisciplinary Technologies Enable Biosynthesis and Discovery of a New Antibiotic, Keyicin

Advances in genomics and metabolomics have made clear in recent years that microbial biosynthetic capacities on Earth far exceed previous expectations. This is attributable, in part, to the realization that most microbial natural product (NP) producers harbor biosynthetic machineries not readily ame...

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Veröffentlicht in:ACS Chem Biol
Hauptverfasser: Adnani, Navid, Chevrette, Marc, Adibhatla, Srikar N., Zhang, Fan, Yu, Qing, Braun, Doug R., Nelson, Justin, Simpkins, Scott W., McDonald, Bradon R., Myers, Chad L., Piotrowski, Jeff S., Thompson, Christopher J., Currie, Cameron R., Li, Lingjun, Rajski, Scott R., Bugni, Tim S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5973552/
https://ncbi.nlm.nih.gov/pubmed/29121465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00688
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