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Omics Technologies to Understand Activation of a Biosynthetic Gene Cluster in Micromonospora sp. WMMB235: Deciphering Keyicin Biosynthesis

[Image: see text] DNA sequencing of a large collection of bacterial genomes reveals a wealth of orphan biosynthetic gene clusters (BGCs) with no identifiable products. BGC silencing, for those orphan clusters that are truly silent, rather than those whose products have simply evaded detection and cl...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Acharya, Deepa, Miller, Ian, Cui, Yusi, Braun, Doug R., Berres, Mark E., Styles, Matthew J., Li, Lingjun, Kwan, Jason, Rajski, Scott R., Blackwell, Helen E., Bugni, Tim S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591704/
https://ncbi.nlm.nih.gov/pubmed/31120241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00223
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