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Nitric oxide stimulates cellular degradation of human CYP51A1, the highly conserved lanosterol 14α-demethylase
Nitric oxide (NO) is known to down-regulate drug metabolizing cytochrome P450 enzymes in an enzyme-selective manner. Ubiquitin-proteasome dependent and independent pathways have been reported. Here we studied the regulation of expression of human CYP51A1, the lanosterol 14α-demethylase required for...
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| Publicado no: | Biochem J |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5972552/ https://ncbi.nlm.nih.gov/pubmed/28830911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170459 |
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