Altered skeletal muscle mitochondrial phenotype in COPD: disease vs. disuse

Patients with chronic obstructive pulmonary disease (COPD) exhibit an altered skeletal muscle mitochondrial phenotype, which often includes reduced mitochondrial density, altered respiratory function, and elevated oxidative stress. As this phenotype may be explained by the sedentary lifestyle that c...

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Veröffentlicht in:J Appl Physiol (1985)
Hauptverfasser: Gifford, Jayson R., Trinity, Joel D., Kwon, Oh-Sung, Layec, Gwenael, Garten, Ryan S., Park, Song-Young, Nelson, Ashley D., Richardson, Russell S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972462/
https://ncbi.nlm.nih.gov/pubmed/29357496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00788.2017
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