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Oxygen availability and skeletal muscle oxidative capacity in patients with peripheral artery disease: implications from in vivo and in vitro assessments

Evidence suggests that the peak skeletal muscle mitochondrial ATP synthesis rate (V(max)) in patients with peripheral artery disease (PAD) may be attenuated due to disease-related impairments in O(2) supply. However, in vitro assessments suggest intrinsic deficits in mitochondrial respiration despit...

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Bibliografische gegevens
Gepubliceerd in:Am J Physiol Heart Circ Physiol
Hoofdauteurs: Hart, Corey R., Layec, Gwenael, Trinity, Joel D., Le Fur, Yann, Gifford, Jayson R., Clifton, Heather L., Richardson, Russell S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230899/
https://ncbi.nlm.nih.gov/pubmed/29932772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00641.2017
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