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Ablation of Type III Adenylyl Cyclase in Mice Causes Reduced Neuronal Activity, Altered Sleep Pattern, and Depression-Like Phenotypes
BACKGROUND: Although major depressive disorder (MDD) has low heritability, a genome-wide association study in humans has recently implicated type 3 adenylyl cyclase (AC3, ADCY3) in MDD. Moreover, the expression level of AC3 in blood has been considered as a MDD biomarker in humans, but there is lack...
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| Publicado no: | Biol Psychiatry |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5972377/ https://ncbi.nlm.nih.gov/pubmed/26868444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.12.012 |
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