Diabetes Worsens Skeletal Muscle Mitochondrial Function, Oxidative Stress, and Apoptosis After Lower-Limb Ischemia-Reperfusion: Implication of the RISK and SAFE Pathways?

Objectives: Diabetic patients respond poorly to revascularization for peripheral arterial disease (PAD) but the underlying mechanisms are not well understood. We aimed to determine whether diabetes worsens ischemia-reperfusion (IR)-induced muscle dysfunction and the involvement of endogenous protect...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Pottecher, Julien, Adamopoulos, Chris, Lejay, Anne, Bouitbir, Jamal, Charles, Anne-Laure, Meyer, Alain, Singer, Mervyn, Wolff, Valerie, Diemunsch, Pierre, Laverny, Gilles, Metzger, Daniel, Geny, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972292/
https://ncbi.nlm.nih.gov/pubmed/29872405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00579
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